Using of electrochemical methods for studying of metallothionein content in the human blood serum of a patient poisoned by lead and treated by platinum.

نویسندگان

  • Jitka Petrlová
  • Ondrej Blastík
  • Richard Průsa
  • Jirí Kukacka
  • David Potĕsil
  • Radka Mikelová
  • Vojtĕch Adam
  • Josef Zehnálek
  • René Kizek
چکیده

Metallothioneins belong to the group of intracellular, high molecular and cysteine-rich proteins whose content increase with increasing concentration of a heavy metal. Here we applied the adsorptive transfer stripping differential pulse voltammetry Brdicka reaction for the determination of metallothionein in human blood serum of patient poisoned by lead and/or treated by platinum. The increased metallothionein concentrations in both cases were observed.

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عنوان ژورنال:
  • Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia

دوره 149 2  شماره 

صفحات  -

تاریخ انتشار 2005